Death of new microRNA genes in Drosophila via gradual loss of fitness advantages

The prevalence of de novo coding genes is controversial due to length and coding constraints. Noncoding genes, especially small ones, are freer to evolve de novo by comparison. The best examples are microRNAs (miRNAs), a large class of regulatory molecules ∼22 nt in length. Here, we study six de nov...

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Publicado en:Genome Res
Autores principales: Lu, Guang-An, Zhao, Yixin, Yang, Hao, Lan, Ao, Shi, Suhua, Liufu, Zhongqi, Huang, Yumei, Tang, Tian, Xu, Jin, Shen, Xu, Wu, Chung-I
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120634/
https://ncbi.nlm.nih.gov/pubmed/30049791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.233809.117
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