Life after ponatinib failure: outcomes of chronic and accelerated phase CML patients who discontinued ponatinib in the salvage setting

BACKGROUND: Ponatinib is a pan-tyrosine kinase inhibitor (TKI) with efficacy in multi-refractory CML patients who have failed other TKIs. Despite excellent response rates, resistance or intolerance may develop. METHODS: We conducted a retrospective review of the outcome of patients with chronic (CP)...

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Published in:Leuk Lymphoma
Main Authors: Boddu, Prajwal, Shah, Abdul Rashid, Borthakur, Gautam, Verstovsek, Srdan, Garcia-Manero, Guillermo, Daver, Naval, Kadia, Tapan, Ravandi, Farhad, Jain, Nitin, Alhuraiji, Ahmad, Burger, Jan, Kornblau, Steven, Pierce, Sherry, Dellasala, Sara, Jabbour, Elias, Kantarjian, Hagop, Cortes, Jorge
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120342/
https://ncbi.nlm.nih.gov/pubmed/28972430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2017.1379076
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