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Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer

We aimed to refine the value of CDX2 as an independent prognostic and predictive biomarker in colorectal cancer (CRC) according to disease stage and chemotherapy sensitivity in preclinical models. CDX2 expression was evaluated in 1045 stage I–IV primary CRCs by gene expression (n = 403) or immunohis...

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Dettagli Bibliografici
Pubblicato in:Mol Oncol
Autori principali: Bruun, Jarle, Sveen, Anita, Barros, Rita, Eide, Peter W., Eilertsen, Ina, Kolberg, Matthias, Pellinen, Teijo, David, Leonor, Svindland, Aud, Kallioniemi, Olli, Guren, Marianne G., Nesbakken, Arild, Almeida, Raquel, Lothe, Ragnhild A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120232/
https://ncbi.nlm.nih.gov/pubmed/29900672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12347
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