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Alpha-synuclein, Proteotoxicity and Parkinson's Disease: Search for Neuroprotective Therapy

BACKGROUND: There is a growing body of evidence in animal and cell based models of Parkinson's disease (PD) to suggest that overexpression and / or abnormal accumulation and aggregation of α-synuclein can trigger neuronal death. This important role of α-synuclein in PD pathogenesis is supported...

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Bibliografske podrobnosti
izdano v:Curr Neuropharmacol
Main Authors: Ganguly, Upasana, Chakrabarti, Sankha Shubhra, Kaur, Upinder, Mukherjee, Anwesha, Chakrabarti, Sasanka
Format: Artigo
Jezik:Inglês
Izdano: Bentham Science Publishers 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120113/
https://ncbi.nlm.nih.gov/pubmed/29189163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X15666171129100944
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