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Impact of FMR1 Premutation on Neurobehavior and Bioenergetics in Young Monozygotic Twins

Mitochondrial dysfunction (MD) has been identified in lymphocytes, fibroblasts and brain samples from adults carrying a 55–200 CGG expansion in the fragile X mental retardation 1 (FMR1) gene (premutation; PM); however, limited data are available on the bioenergetics of pediatric carriers. Here we di...

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Veröffentlicht in:Front Genet
Hauptverfasser: Napoli, Eleonora, Schneider, Andrea, Hagerman, Randi, Song, Gyu, Wong, Sarah, Tassone, Flora, Giulivi, Cecilia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6119880/
https://ncbi.nlm.nih.gov/pubmed/30210529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00338
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