A common glaucoma-risk variant of SIX6 alters retinal nerve fiber layer and optic disc measures in a European population: The EPIC-Norfolk Eye Study

PURPOSE: A common missense variant in the SIX6 gene (rs33912345) is strongly associated with primary open-angle glaucoma (POAG). We aimed to examine the association of rs33912345 with optic disc and retinal nerve fiber layer (RNFL) measures in a European population. METHODS: We examined participants...

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Detalhes bibliográficos
Publicado no:J Glaucoma
Main Authors: Khawaja, Anthony P., Chan, Michelle P. Y., Yip, Jennifer L. Y., Broadway, David C., Garway-Heath, David F., Viswanathan, Ananth C., Luben, Robert, Hayat, Shabina, Hauser, Michael A., Wareham, Nicholas J., Khaw, Kay-Tee, Fortune, Brad, Allingham, R Rand, Foster, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6119604/
https://ncbi.nlm.nih.gov/pubmed/30005032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/IJG.0000000000001026
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