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Unleashing endogenous TNF-alpha as a cancer immunotherapeutic

Tumor necrosis factor (TNF)-alpha was originally identified in the 1970s as the serum mediator of innate immunity capable of inducing hemorrhagic necrosis in tumors. Today, a wide spectrum of biological activities have been attributed to this molecule, and clinical translation has mainly occurred no...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Josephs, Steven F., Ichim, Thomas E., Prince, Stephen M., Kesari, Santosh, Marincola, Francesco M., Escobedo, Anton Rolando, Jafri, Amir
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6119315/
https://ncbi.nlm.nih.gov/pubmed/30170620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1611-7
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