A loop-mediated isothermal amplification assay for the detection and quantification of JC polyomavirus in cerebrospinal fluid: a diagnostic and clinical management tool and technique for progressive multifocal leukoencephalopathy

BACKGROUND: JC polyomavirus (JCV) is the causative agent of progressive multifocal leukoencephalopathy (PML), a demyelinating disease of the central nervous system in immunosuppressed patients. PML usually has a poor prognosis. Detection and quantification of the JCV genome in cerebrospinal fluid (C...

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Detalhes bibliográficos
Publicado no:Virol J
Main Authors: Kinoshita, Hitomi, Nakamichi, Kazuo, Lim, Chang-Kweng, Takayama-Ito, Mutsuyo, Wang, Lixin, Iizuka, Itoe, Kurane, Ichiro, Saijo, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6119251/
https://ncbi.nlm.nih.gov/pubmed/30170628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-018-1046-z
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