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Ca(2+)-binding protein NECAB2 facilitates inflammatory pain hypersensitivity

Pain signals are transmitted by multisynaptic glutamatergic pathways. Their first synapse between primary nociceptors and excitatory spinal interneurons gates the sensory load. In this pathway, glutamate release is orchestrated by Ca(2+)-sensor proteins, with N-terminal EF-hand Ca(2+)-binding protei...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Zhang, Ming-Dong, Su, Jie, Adori, Csaba, Cinquina, Valentina, Malenczyk, Katarzyna, Girach, Fatima, Peng, Changgeng, Ernfors, Patrik, Löw, Peter, Borgius, Lotta, Kiehn, Ole, Watanabe, Masahiko, Uhlén, Mathias, Mitsios, Nicholas, Mulder, Jan, Harkany, Tibor, Hökfelt, Tomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118643/
https://ncbi.nlm.nih.gov/pubmed/29893745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI120913
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