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Recurrent hypoglycemia inhibits the counterregulatory response by suppressing adrenal activity

Hypoglycemia activates the counterregulatory response (CRR), a neural-endocrine reflex that restores euglycemia. Although effective if occasionally activated, repeated induction of the CRR leads to a decline in responsiveness and prolonged exposure to hypoglycemia. The mechanism underlying this impa...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Ma, Yunbing, Wang, Qian, Joe, Debria, Wang, Manqi, Whim, Matthew D.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118578/
https://ncbi.nlm.nih.gov/pubmed/30080182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI91921
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