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Spectroscopic and molecular modeling studies of binding interaction between bovine serum albumin and roflumilast
BACKGROUND: The binding interaction between bovine serum albumin (BSA) and roflumilast (ROF) was explored in this study. The binding of drugs to albumin plays a vital role in their pharmacokinetics and pharmacodynamics in vivo. The mechanisms involved in the interaction between BSA and ROF was studi...
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| Publicado no: | Drug Des Devel Ther |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6118266/ https://ncbi.nlm.nih.gov/pubmed/30214151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S169697 |
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