Spectroscopic and molecular modeling studies of binding interaction between bovine serum albumin and roflumilast

BACKGROUND: The binding interaction between bovine serum albumin (BSA) and roflumilast (ROF) was explored in this study. The binding of drugs to albumin plays a vital role in their pharmacokinetics and pharmacodynamics in vivo. The mechanisms involved in the interaction between BSA and ROF was studi...

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Библиографические подробности
Опубликовано в: :Drug Des Devel Ther
Главные авторы: Wani, Tanveer A, Bakheit, Ahmed H, Ansari, Mohammed Nazam, Al-Majed, Abdul-Rahman A, Al-Qahtani, Bakr M, Zargar, Seema
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2018
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118266/
https://ncbi.nlm.nih.gov/pubmed/30214151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S169697
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