Clonally Expanded Decidual Effector Regulatory T Cells Increase in Late Gestation of Normal Pregnancy, but Not in Preeclampsia, in Humans

Background: Regulatory T (Treg) cells are necessary for the maintenance of allogenic pregnancy. However, the repertoire of effector Treg cells at the feto-maternal interface in human pregnancy remains unknown. Our objective was to study T cell receptor (TCR) repertoires of Treg cells during pregnanc...

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Pubblicato in:Front Immunol
Autori principali: Tsuda, Sayaka, Zhang, Xiaoxin, Hamana, Hiroshi, Shima, Tomoko, Ushijima, Akemi, Tsuda, Kei, Muraguchi, Atsushi, Kishi, Hiroyuki, Saito, Shigeru
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118230/
https://ncbi.nlm.nih.gov/pubmed/30197648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01934
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