Exposure of Endothelium to Biomimetic Flow Waveforms Yields Identification of miR-199a-5p as a Potent Regulator of Arteriogenesis

Arteriogenesis, the growth of endogenous collateral arteries bypassing arterial occlusion(s), is a fundamental shear stress-induced adaptation with implications for treating peripheral arterial disease (PAD). Nonetheless, endothelial mechano-signaling during arteriogenesis is incompletely understood...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther Nucleic Acids
Hauptverfasser: Heuslein, Joshua L., Gorick, Catherine M., McDonnell, Stephanie P., Song, Ji, Annex, Brian H., Price, Richard J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118158/
https://ncbi.nlm.nih.gov/pubmed/30153567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.08.001
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