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A Robust Liposomal Platform for Direct Colorimetric Detection of Sphingomyelinase Enzyme and Inhibitors

[Image: see text] The enzyme sphingomyelinase (SMase) is an important biomarker for several diseases such as Niemann Pick’s, atherosclerosis, multiple sclerosis, and HIV. We present a two-component colorimetric SMase activity assay that is more sensitive and much faster than currently available comm...

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Detalhes bibliográficos
Publicado no:ACS Nano
Main Authors: Holme, Margaret N., Rana, Subinoy, Barriga, Hanna M. G., Kauscher, Ulrike, Brooks, Nicholas J., Stevens, Molly M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117748/
https://ncbi.nlm.nih.gov/pubmed/30080036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.8b03308
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