The Long Noncoding RNA MEG3 and its Target miR-147 Regulate JAK/STAT Pathway in Advanced Chronic Myeloid Leukemia

BACKGROUND: Long non-coding (lnc) RNAs plays an important role in chronic myeloid leukemia (CML). In this study, we aimed to uncover the mechanism of the lncRNA maternally expressed 3 (MEG3) and its target microRNA-147 (miR-147) in CML. METHODS: Sixty CML patients and 10 healthy donors were included...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Li, Zi-ye, Yang, Lin, Liu, Xiao-jun, Wang, Xing-zhe, Pan, Yu-xia, Luo, Jian-min
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117736/
https://ncbi.nlm.nih.gov/pubmed/30072211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.07.013
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