Syntrophin-dependent expression and localization of Aquaporin-4 water channel protein

The Aquaporin-4 (AQP4) water channel contributes to brain water homeostasis in perivascular astrocyte endfeet where it is concentrated. We postulated that AQP4 is tethered at this site by binding of the AQP4 C terminus to the PSD95-Discs large-ZO1 (PDZ) domain of syntrophin, a component of the dystr...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Neely, John D., Amiry-Moghaddam, Mahmood, Ottersen, Ole Petter, Froehner, Stanley C., Agre, Peter, Adams, Marvin E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC61176/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11717465/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.241508198
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