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Nano-particle engineered atorvastatin delivery to support mesenchymal stem cell survival in infarcted myocardium

Atorvastatin (ATV) may support mesenchymal stem cells (MSC) survival in post-infarct myocardium (MI) as inflammatory reactions, oxidative stress and hypoxia condition get started in such tissues after damage. However, limited aqueous insolubility and rapid first-pass metabolism reduce the systemic a...

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Bibliographische Detailangaben
Veröffentlicht in:Saudi J Biol Sci
Hauptverfasser: Yao, Guang-tao, Song, Li-ping, Xue, Wan-hua, Su, Guo-hai, Ning, Ai-hua, Wang, Jin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117435/
https://ncbi.nlm.nih.gov/pubmed/30174496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sjbs.2017.03.015
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