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Luciferase-induced photoreductive uncaging of small-molecule effectors

Bioluminescence resonance energy transfer (BRET) is extensively used to study dynamic systems and has been utilized in sensors for studying protein proximity, metabolites, and drug concentrations. Herein, we demonstrate that BRET can activate a ruthenium-based photocatalyst which performs bioorthogo...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Lindberg, Eric, Angerani, Simona, Anzola, Marcello, Winssinger, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117273/
https://ncbi.nlm.nih.gov/pubmed/30166547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05916-9
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