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Chromatin Loop Formation Induced by a Subtelomeric Protosilencer Represses EPA Genes in Candida glabrata

Adherence, an important virulence factor, is mediated by the EPA (Epithelial Adhesin) genes in the opportunistic pathogen Candida glabrata. Expression of adhesin-encoding genes requires tight regulation to respond to harsh environmental conditions within the host. The majority of EPA genes are local...

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Publicat a:Genetics
Autors principals: López-Fuentes, Eunice, Hernández-Hernández, Grecia, Castanedo, Leonardo, Gutiérrez-Escobedo, Guadalupe, Oktaba, Katarzyna, De las Peñas, Alejandro, Castaño, Irene
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6116953/
https://ncbi.nlm.nih.gov/pubmed/30002080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.301202
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