Enhanced IL-6/phosphorylated STAT3 signaling is related to the imbalance of circulating T follicular helper/T follicular regulatory cells in patients with rheumatoid arthritis

BACKGROUND: Follicular helper T (Tfh) cells are specialized in helping B lymphocytes, which play a central role in autoimmune diseases that have a major B cell component, such as in rheumatoid arthritis (RA). Follicular regulatory T (Tfr) cells control the over-activation of Tfh and B cells in germi...

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Vydáno v:Arthritis Res Ther
Hlavní autoři: Niu, Qian, Huang, Zhuo-chun, Wu, Xiao-juan, Jin, Ya-xiong, An, Yun-fei, Li, Ya-mei, Xu, Huan, Yang, Bin, Wang, Lan-lan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6116385/
https://ncbi.nlm.nih.gov/pubmed/30157931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1690-0
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