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RSPO3 impairs barrier function of human vascular endothelial monolayers and synergizes with pro-inflammatory IL-1
BACKGROUND: Endothelial barrier dysfunction characterized by hyperpermeability of the vascular endothelium is a key factor in the pathogenesis of chronic inflammatory diseases and affects clinical outcomes. In states of chronic inflammation, mediators secreted by activated immune cells or vascular e...
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| Publicado en: | Mol Med |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6116367/ https://ncbi.nlm.nih.gov/pubmed/30157748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-018-0048-z |
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