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The synthetic enantiomer of pregnenolone sulfate is very active on memory in rats and mice, even more so than its physiological neurosteroid counterpart: Distinct mechanisms?

The demonstration that the neurosteroid pregnenolone sulfate (PREGS) is active on memory function at both the physiological and pharmacological levels led to us examining in detail the effects of the steroid on spatial working memory by using a two-trial recognition task in a Y-maze, a paradigm base...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Akwa, Yvette, Ladurelle, Nathalie, Covey, Douglas F., Baulieu, Etienne-Emile
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC61162/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11717462/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.241503698
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