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The Precision Control of Autophagic Flux and Vesicle Dynamics—A Micropattern Approach

Autophagy failure is implicated in age-related human disease. A decrease in the rate of protein degradation through the entire autophagy pathway, i.e., autophagic flux, has been associated with the onset of cellular proteotoxity and cell death. Although the precision control of autophagy as a pharma...

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Dettagli Bibliografici
Pubblicato in:Cells
Autori principali: du Toit, André, De Wet, Sholto, Hofmeyr, Jan-Hendrik S., Müller-Nedebock, Kristian K., Loos, Ben
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6116198/
https://ncbi.nlm.nih.gov/pubmed/30081508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7080094
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