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LY2157299 Monohydrate, a TGF-βR1 Inhibitor, Suppresses Tumor Growth and Ascites Development in Ovarian Cancer

Transforming growth factor beta (TGF-β) signaling has pleiotropic functions regulating cancer initiation, development, and metastasis, and also plays important roles in the interaction between stromal and cancer cells, making the pathway a potential therapeutic target. LY2157299 monohydrate (LY), an...

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Foilsithe in:Cancers (Basel)
Main Authors: Zhang, Qing, Hou, Xiaonan, Evans, Bradley J., VanBlaricom, Jamison L., Weroha, Saravut J., Cliby, William A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6115954/
https://ncbi.nlm.nih.gov/pubmed/30087253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10080260
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