Pretransplant C3d-Fixing Donor-Specific Anti-HLA Antibodies Are Not Associated with Increased Risk for Kidney Graft Failure

Background Complement-fixing antibodies against donor HLA are considered a contraindication for kidney transplant. A modification of the IgG single-antigen bead (SAB) assay allows detection of anti-HLA antibodies that bind C3d. Because early humoral graft rejection is considered to be complement med...

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Publicat a:J Am Soc Nephrol
Autors principals: Kamburova, Elena G., Wisse, Bram W., Joosten, Irma, Allebes, Wil A., van der Meer, Arnold, Hilbrands, Luuk B., Baas, Marije C., Spierings, Eric, Hack, Cornelis E., van Reekum, Franka E., van Zuilen, Arjan D., Verhaar, Marianne C., Bots, Michiel L., Drop, Adriaan C.A.D., Plaisier, Loes, Seelen, Marc A.J., Sanders, Jan Stephan, Hepkema, Bouke G., Lambeck, Annechien J.A., Bungener, Laura B., Roozendaal, Caroline, Tilanus, Marcel G.J., Voorter, Christina E., Wieten, Lotte, van Duijnhoven, Elly M., Gelens, Mariëlle A.C.J., Christiaans, Maarten H.L., van Ittersum, Frans J., Nurmohamed, Shaikh A., Lardy, Neubury M., Swelsen, Wendy, van der Pant, Karlijn A.M.I., van der Weerd, Neelke C., ten Berge, Ineke J.M., Bemelman, Frederike J., Hoitsma, Andries J., van der Boog, Paul J.M., de Fijter, Johan W., Betjes, Michiel G.H., Heidt, Sebastiaan, Roelen, Dave L., Claas, Frans H., Otten, Henny G.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2018
Matèries:
Rapid Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6115667/
https://ncbi.nlm.nih.gov/pubmed/30049681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018020205
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