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Full-Profile Pharmacokinetic Study of High Dose Baclofen in Subjects With Alcohol Use Disorder

Baclofen a gamma amino-butyric acid type B (GABA-B) receptor agonist, which has raised some interest for the treatment of alcohol use disorder (AUD), occasionally at dose up to 300 mg/d. We conducted the first full-profile pharmacokinetic study on baclofen in AUD subjects, up to the oral daily dose...

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Foilsithe in:Front Psychiatry
Main Authors: Simon, Nicolas, Moirand, Romain, Dematteis, Maurice, Bordet, Régis, Deplanque, Dominique, Rolland, Benjamin
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6115517/
https://ncbi.nlm.nih.gov/pubmed/30190685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2018.00385
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