Increased Formation of Follicular Antrum in Aquaporin-8-Deficient Mice Is Due to Defective Proliferation and Migration, and Not Steroidogenesis of Granulosa Cells

Aquaporin-8 (AQP8) is a water channel protein expressed exclusively in granulosa cells (GCs) in mouse ovary. Our previous studies of AQP8-deficient (AQP8(-/-)) mice demonstrated that AQP8 participates in folliculogenesis, including in the formation of follicles, ovulation, and atresia. However, its...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Wang, Dejiang, Di, Xiangjun, Wang, Jie, Li, Miao, Zhang, Di, Hou, Yaxin, Hu, Jiao, Zhang, Ge, Zhang, He, Sun, Meiyan, Meng, Xiangyu, Sun, Bo, Jiang, Chunlai, Ma, Tonghui, Su, Weiheng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6115504/
https://ncbi.nlm.nih.gov/pubmed/30190683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01193
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