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Immuno-Oncology: Emerging Targets and Combination Therapies
Host immunity recognizes and eliminates most early tumor cells, yet immunological checkpoints, exemplified by CTLA-4, PD-1, and PD-L1, pose a significant obstacle to effective antitumor immune responses. T-lymphocyte co-inhibitory pathways influence intensity, inflammation and duration of antitumor...
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| Publicado no: | Front Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6115503/ https://ncbi.nlm.nih.gov/pubmed/30191140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00315 |
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