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HGF-mediated crosstalk between cancer-associated fibroblasts and MET-unamplified gastric cancer cells activates coordinated tumorigenesis and metastasis

Cancer-associated fibroblasts (CAFs) are important components of tumor stroma and play a key role in tumor progression. CAFs involve in crosstalk with tumor cells through various kinds of cytokines. In the present study, we screened hepatocyte growth factor (HGF) as a cytokine predominantly originat...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Ding, Xusheng, Ji, Jun, Jiang, Jinling, Cai, Qu, Wang, Chao, Shi, Min, Yu, Yingyan, Zhu, Zhenggang, Zhang, Jun
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6115420/
https://ncbi.nlm.nih.gov/pubmed/30158543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0922-1
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