Prolyl isomerase Pin1: a promoter of cancer and a target for therapy

Pin1 is the only known peptidyl-prolyl cis–trans isomerase (PPIase) that specifically recognizes and isomerizes the phosphorylated Serine/Threonine-Proline (pSer/Thr-Pro) motif. The Pin1-mediated structural transformation posttranslationally regulates the biofunctions of multiple proteins. Pin1 is i...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Chen, Yang, Wu, Ya-ran, Yang, Hong-ying, Li, Xin-zhe, Jie, Meng-meng, Hu, Chang-jiang, Wu, Yu-yun, Yang, Shi-ming, Yang, Ying-bin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
Soggetti:
Review Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6115400/
https://ncbi.nlm.nih.gov/pubmed/30158600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0844-y
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