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Inhibition of voltage-dependent K(+) current in rabbit coronary arterial smooth muscle cells by the class Ic antiarrhythmic drug propafenone

In this study, we demonstrated the inhibitory effect of the Class Ic antiarrhythmic agent propafenone on voltage-dependent K(+) (Kv) channels using freshly isolated coronary artery smooth muscle cells from rabbits. The Kv current amplitude was progressively inhibited by propafenone in a dose-depende...

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Bibliographic Details
Published in:Korean J Physiol Pharmacol
Main Authors: An, Jin Ryeol, Li, Hongliang, Seo, Mi Seon, Park, Won Sun
Format: Artigo
Language:Inglês
Published: The Korean Physiological Society and The Korean Society of Pharmacology 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6115351/
https://ncbi.nlm.nih.gov/pubmed/30181706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2018.22.5.597
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