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Long read sequencing reveals poxvirus evolution through rapid homogenization of gene arrays

Poxvirus adaptation can involve combinations of recombination-driven gene copy number variation and beneficial single nucleotide variants (SNVs) at the same loci. How these distinct mechanisms of genetic diversification might simultaneously facilitate adaptation to host immune defenses is unknown. W...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Sasani, Thomas A, Cone, Kelsey R, Quinlan, Aaron R, Elde, Nels C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6115191/
https://ncbi.nlm.nih.gov/pubmed/30156554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35453
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