E-cadherin bridges cell polarity and spindle orientation to ensure prostate epithelial integrity and prevent carcinogenesis in vivo

Cell polarity and correct mitotic spindle positioning are essential for the maintenance of a proper prostate epithelial architecture, and disruption of the two biological features occurs at early stages in prostate tumorigenesis. However, whether and how these two epithelial attributes are connected...

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Vydáno v:PLoS Genet
Hlavní autoři: Wang, Xue, Dong, Baijun, Zhang, Kai, Ji, Zhongzhong, Cheng, Chaping, Zhao, Huifang, Sheng, Yaru, Li, Xiaoxia, Fan, Liancheng, Xue, Wei, Gao, Wei-Qiang, Zhu, Helen He
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6115016/
https://ncbi.nlm.nih.gov/pubmed/30118484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007609
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