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An automated screening method for detecting compounds with goitrogenic activity using transgenic zebrafish embryos

The knowledge on environmentally relevant chemicals that may interfere with thyroid signaling is scarce. Here, we present a method for the screening of goitrogens, compounds that disrupt the thyroid gland function, based on the automatic orientation of zebrafish in a glass capillary and a subsequent...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jarque, Sergio, Fetter, Eva, Veneman, Wouter J., Spaink, Herman P., Peravali, Ravindra, Strähle, Uwe, Scholz, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6114901/
https://ncbi.nlm.nih.gov/pubmed/30157258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203087
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