Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B

Semaphorins SEMA3B and its homologue SEMA3F are 3p21.3 candidate tumor suppressor genes (TSGs), the expression of which is frequently lost in lung cancers. To test the TSG candidacy of SEMA3B and SEMA3F, we transfected them into lung cancer NCI-H1299 cells, which do not express either gene. Colony f...

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Autors principals: Tomizawa, Yoshio, Sekido, Yoshitaka, Kondo, Masashi, Gao, Boning, Yokota, Jun, Roche, Joëlle, Drabkin, Harry, Lerman, Michael I., Gazdar, Adi F., Minna, John D.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC61148/
https://ncbi.nlm.nih.gov/pubmed/11717452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231490898
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