Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B

Semaphorins SEMA3B and its homologue SEMA3F are 3p21.3 candidate tumor suppressor genes (TSGs), the expression of which is frequently lost in lung cancers. To test the TSG candidacy of SEMA3B and SEMA3F, we transfected them into lung cancer NCI-H1299 cells, which do not express either gene. Colony f...

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Main Authors: Tomizawa, Yoshio, Sekido, Yoshitaka, Kondo, Masashi, Gao, Boning, Yokota, Jun, Roche, Joëlle, Drabkin, Harry, Lerman, Michael I., Gazdar, Adi F., Minna, John D.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC61148/
https://ncbi.nlm.nih.gov/pubmed/11717452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231490898
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