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Targeting the autophagy in bone marrow stromal cells overcomes resistance to vorinostat in chronic lymphocytic leukemia

BACKGROUND: The bone marrow microenvironment constitutes a sanctuary for leukemia cells. Recent evidence indicates that environment-mediated drug resistance arises from a reciprocal influence between tumor cells and the surrounding stroma. The present study aimed to investigate the effect of chronic...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Ding, Lu, Zhang, Wan, Yang, Lili, Pelicano, Helene, Zhou, Kaiwen, Yin, Ran, Huang, Ruibin, Zeng, Junyi
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6114474/
https://ncbi.nlm.nih.gov/pubmed/30210236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S170392
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