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Multiple imputation for patient reported outcome measures in randomised controlled trials: advantages and disadvantages of imputing at the item, subscale or composite score level

BACKGROUND: Missing data can introduce bias in the results of randomised controlled trials (RCTs), but are typically unavoidable in pragmatic clinical research, especially when patient reported outcome measures (PROMs) are used. Traditionally applied to the composite PROMs score of multi-item instru...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Med Res Methodol
Prif Awduron: Rombach, Ines, Gray, Alastair M., Jenkinson, Crispin, Murray, David W., Rivero-Arias, Oliver
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6114240/
https://ncbi.nlm.nih.gov/pubmed/30153796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-018-0542-6
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