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Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3)

Steroid hormones are central regulators of a variety of biological processes. According to the free hormone hypothesis, steroids enter target cells by passive diffusion. However, recently we demonstrated that 25(OH) vitamin D(3) complexed to its plasma carrier, the vitamin D-binding protein, enters...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Nykjaer, Anders, Fyfe, John C., Kozyraki, Renata, Leheste, Jörg-Robert, Jacobsen, Christian, Nielsen, Morten S., Verroust, Pierre J., Aminoff, Maria, de la Chapelle, Albert, Moestrup, Søren K., Ray, Rahul, Gliemann, Jørgen, Willnow, Thomas E., Christensen, Erik I.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC61138/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11717447/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.241516998
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