A Phase I, Single Ascending Dose Study of Cimaglermin Alfa (Neuregulin 1β3) in Patients With Systolic Dysfunction and Heart Failure

A first-in-human, phase 1, double blind, placebo-controlled, single ascending dose study examined the safety, tolerability, and exploratory efficacy of intravenous infusion of a recombinant growth factor, cimaglermin alfa, in patients with heart failure and left ventricular systolic dysfunction (LVS...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JACC Basic Transl Sci
Egile Nagusiak: Lenihan, Daniel J., Anderson, Sarah A., Lenneman, Carrie Geisberg, Brittain, Evan, Muldowney, James A.S., Mendes, Lisa, Zhao, Ping Z., Iaci, Jennifer, Frohwein, Stephen, Zolty, Ronald, Eisen, Andrew, Sawyer, Douglas B., Caggiano, Anthony O.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2016
Gaiak:
CLINICAL RESEARCH
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113538/
https://ncbi.nlm.nih.gov/pubmed/30167542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2016.09.005
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