Phosphorylation of ULK1 affects autophagosome fusion and links chaperone-mediated autophagy to macroautophagy

The Unc-51 like autophagy activating kinase 1 (ULK1) complex plays a central role in the initiation stage of autophagy. However, the function of ULK1 in the late stage of autophagy is unknown. Here, we report that ULK1, a central kinase of the ULK1 complex involved in autophagy initiation, promotes...

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Udgivet i:Nat Commun
Main Authors: Wang, Chenyao, Wang, Huafei, Zhang, Deyi, Luo, Wenwen, Liu, Ruilong, Xu, Daqian, Diao, Lei, Liao, Lujian, Liu, Zhixue
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113293/
https://ncbi.nlm.nih.gov/pubmed/30154410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05449-1
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