Transcriptomic Analysis Identifies the Effect of Beta-Blocking Agents on a Molecular Pathway of Contraction in the Heart and Predicts Response to Therapy

Over the last decades, beta-blockers have been a key component of heart failure therapy. However, currently there is no method to identify patients who will benefit from beta-blocking therapy versus those who will be unresponsive or worsen. Furthermore, there is an unmet need to better understand mo...

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Vydáno v:JACC Basic Transl Sci
Hlavní autoři: Heidecker, Bettina, Kittleson, Michelle M., Kasper, Edward K., Wittstein, Ilan S., Champion, Hunter C., Russell, Stuart D., Baughman, Kenneth L., Hare, Joshua M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
Témata:
CLINICAL RESEARCH
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113163/
https://ncbi.nlm.nih.gov/pubmed/30167508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2016.02.001
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