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Enhanced delayed-type hypersensitivity and diminished immediate-type hypersensitivity in mice lacking the inducible VPAC(2) receptor for vasoactive intestinal peptide

Vasoactive intestinal peptide (VIP) and its G protein-coupled receptors, VPAC(1)R and VPAC(2)R, are prominent in the immune system and regulate many aspects of T cell-dependent immunity. In mouse T cells, VPAC(1)R is expressed constitutively, whereas VPAC(2)R is induced by immune stimuli. VPAC(2)R-n...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Goetzl, Edward J., Voice, Julia K., Shen, Sanbing, Dorsam, Glenn, Kong, Yvonne, West, Katrine M., Morrison, Christine F., Harmar, Anthony J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC61131/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11698667/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.241503798
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