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Convection Enhanced Delivery of Polymeric Nanoparticles Encapsulating Chemotherapy in Canines with Spontaneous Supratentorial Tumors

Despite aggressive multimodal treatment, survival for patients with glioblastoma (GBM) remains dismal. One obstacle to improving patient outcome is the difficulty in delivering adequate therapeutic to the CNS due to the presence of the blood brain barrier (BBB). While direct drug infusion by convect...

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Bibliografski detalji
Izdano u:World Neurosurg
Glavni autori: Young, Jacob S., Bernal, Giovanna, Polster, Sean P., Nunez, Luis, Larsen, Gustavo F., Mansour, Nassir, Podell, Michael, Yamini, Bakhtiar
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113082/
https://ncbi.nlm.nih.gov/pubmed/29960096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.wneu.2018.06.114
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