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Dietary 23–hydroxy ursolic acid protects against atherosclerosis and obesity by preventing dyslipidemia-induced monocyte priming and dysfunction

BACKGROUND AND AIMS: We demonstrated that dietary ursolic acid (UA) reduces atherosclerotic lesion size and improves kidney function in diabetic mice. Based on structure-function analyses of naturally occurring UA analogs, we synthesized 23-hydroxy ursolic acid (23-OHUA), a compound with structural...

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Detalhes bibliográficos
Publicado no:Atherosclerosis
Main Authors: Nguyen, Huynh Nga, Ahn, Yong Joo, Medina, Edward Antonio, Asmis, Reto
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113078/
https://ncbi.nlm.nih.gov/pubmed/30015296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2018.06.882
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