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PD1 is expressed on exhausted T cells as well as virus specific memory CD8+ T cells in the bone marrow of myeloma patients

Characterization of CD8+ T cells in the tumor microenvironment (TME) is important to predict responses to checkpoint therapy. The TME in multiple myeloma is the bone marrow, which also is an immune organ where immune responses are generated and memory cells stored. The presence of T cells with other...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sponaas, Anne-Marit, Yang, Rui, Rustad, Even Holth, Standal, Therese, Thoresen, Aud Solvang, Dao Vo, Camilla, Waage, Anders, Slørdahl, Tobias S., Børset, Magne, Sundan, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6112830/
https://ncbi.nlm.nih.gov/pubmed/30174794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25882
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