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Dynamic redox balance directs the oocyte-to-embryo transition via developmentally controlled reactive cysteine changes

The metabolic and redox state changes during the transition from an arrested oocyte to a totipotent embryo remain uncharacterized. Here, we applied state-of-the-art, integrated methodologies to dissect these changes in Drosophila. We demonstrate that early embryos have a more oxidized state than mat...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Petrova, Boryana, Liu, Keke, Tian, Caiping, Kitaoka, Maiko, Freinkman, Elizaveta, Yang, Jing, Orr-Weaver, Terry L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6112717/
https://ncbi.nlm.nih.gov/pubmed/30082411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807918115
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