Structural basis for autoantibody recognition of phosphatidylserine-β2 glycoprotein I and apoptotic cells

Apoptotic cells contain nuclear autoantigens that may initiate a systemic autoimmune response. To explore the mechanism of antibody binding to apoptotic cells, 3H9, a murine autoantibody with dual specificity for phospholipids and DNA, was used. H chain mutants of 3H9 were constructed, expressed as...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Cocca, Brian A., Seal, Samarendra N., D'Agnillo, Paolo, Mueller, Yvonne M., Katsikis, Peter D., Rauch, Joyce, Weigert, Martin, Radic, Marko Z.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2001
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC61126/
https://ncbi.nlm.nih.gov/pubmed/11717440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.241510698
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires