Spermatogonial quantity in human prepubertal testicular tissue collected for fertility preservation prior to potentially sterilizing therapy

STUDY QUESTION: Does chemotherapy exposure (with or without alkylating agents) or primary diagnosis affect spermatogonial quantity in human prepubertal testicular tissue? SUMMARY ANSWER: Spermatogonial quantity is significantly reduced in testes of prepubertal boys treated with alkylating agent ther...

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Veröffentlicht in:Hum Reprod
Hauptverfasser: Stukenborg, J -B, Alves-Lopes, J P, Kurek, M, Albalushi, H, Reda, A, Keros, V, Töhönen, V, Bjarnason, R, Romerius, P, Sundin, M, Norén Nyström, U, Langenskiöld, C, Vogt, H, Henningsohn, L, Mitchell, R T, Söder, O, Petersen, C, Jahnukainen, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6112575/
https://ncbi.nlm.nih.gov/pubmed/30052981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/dey240
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