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Synthesis of functionalized N-acetyl muramic acids to probe bacterial cell wall recycling and biosynthesis

Uridine diphosphate N-acetyl muramic acid (UDP NAM) is a critical intermediate in bacterial peptidoglycan (PG) biosynthesis. As the primary source of muramic acid that shapes the PG backbone, modifications installed at the UDP NAM intermediate can be used to selectively tag and manipulate this polym...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: DeMeester, Kristen E., Liang, Hai, Jensen, Matthew R., Jones, Zachary S., D’Ambrosio, Elizabeth A., Scinto, Samuel L., Zhou, Junhui, Grimes, Catherine L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6112571/
https://ncbi.nlm.nih.gov/pubmed/29986130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b03304
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