Butyrate Protects Mice Against Methionine–Choline-Deficient Diet-Induced Non-alcoholic Steatohepatitis by Improving Gut Barrier Function, Attenuating Inflammation and Reducing Endotoxin Levels

Butyrate exerts protective effects against non-alcoholic steatohepatitis (NASH), but the underlying mechanisms are unclear. We aimed to investigate the role of butyrate-induced gut microbiota and metabolism in NASH development. Sixty-five C57BL/6J mice were divided into four groups (n = 15–17 per gr...

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Bibliografski detalji
Izdano u:Front Microbiol
Glavni autori: Ye, Jianzhong, Lv, Longxian, Wu, Wenrui, Li, Yating, Shi, Ding, Fang, Daiqiong, Guo, Feifei, Jiang, Huiyong, Yan, Ren, Ye, Wanchun, Li, Lanjuan
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Microbiology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6111843/
https://ncbi.nlm.nih.gov/pubmed/30186272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01967
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